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The coumarin anticoagulants include
dicumarol, warfarin sodium (coumadin sodium), warfarin
potassium (Athrombin-K), acenocoumarol
(Sintrom), and phenprocoumon (Liquamar).
The inanedione derivatives are
phenindione (Hedulin), diphenadione (Dipaxin), and anisindione
(Miradon). The pharmacological
properties of oral anticoagulants are identical qualitatively,
but their pharmacokinetic
parameters and their toxicities vary. Racemic warfarin sodium is the
most widely used anticoagulant.
Antithrombotic drugs are used clinically either to prevent the
formation of blood clots within
the circulation (anticoagulant) or to dissolve a clot that has already
formed (thrombolytic).
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