herbalmedicos.blogspot.in
The saliva of the medicinal
leech contains a battery of substances that interfere with the hemostatic
mechanisms of the host. One of
these compounds is hirudin, a potent anticoagulant, which
maintains the fluidity of the
ingested blood and is the most potent inhibitor of thrombin. Upon
binding to thrombin, the cleavage
of fibrinogen and subsequent clot formation are prevented. The
potency and specificity of
hirudin make it a useful antithrombin-III-independent alternative to
heparin for the control of
thrombosis.
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